This page hosts a repository of segmented cells from the thin blood smear slide images from the Malaria Screener research activity. To reduce the burden for microscopists in resource-constrained regions and improve diagnostic accuracy, researchers at the Lister Hill National Center for Biomedical Communications (LHNCBC), part of National Library of Medicine (NLM), have developed a mobile application that runs on a standard Android smartphone attached to a conventional light microscope. Giemsa-stained thin blood smear slides from 150 P. falciparum-infected and 50 healthy patients were collected and photographed at Chittagong Medical College Hospital, Bangladesh. The smartphone’s built-in camera acquired images of slides for each microscopic field of view. The images were manually annotated by an expert slide reader at the Mahidol-Oxford Tropical Medicine Research Unit in Bangkok, Thailand. The de-identified images and annotations are archived at NLM (IRB#12972). We applied a level-set based algorithm to detect and segment the red blood cells. The dataset contains a total of 27,558 cell images with equal instances of parasitized and uninfected cells. An instance of how the patient-ID is encoded into the cell name is shown herewith: “P1” denotes the patient-ID for the cell labeled “C33P1thinF_IMG_20150619_114756a_cell_179.png”. We have also included the CSV files containing the Patient-ID to cell mappings for the parasitized and uninfected classes. The CSV file for the parasitized class contains 151 patient-ID entries. The slide images for the parasitized patient-ID “C47P8thinOriginal” are read from two different microscope models (Olympus and Motif). The CSV file for the uninfected class contains 201 entries since the normal cells from the infected patients’ slides also make it to the normal cell category (151+50 = 201).
The data appears along with the publication:
Rajaraman S, Antani SK, Poostchi M, Silamut K, Hossain MA, Maude, RJ, Jaeger S, Thoma GR. (2018) Pre-trained convolutional neural networks as feature extractors toward improved Malaria parasite detection in thin blood smear images. PeerJ6:e4568 https://doi.org/10.7717/peerj.4568
An improvement in performance has been recently reported using deep neural ensembles toward malaria parasite detection in thin-blood smear images and is published in the PeerJ journal as cited herewith:
Rajaraman S, Jaeger S, Antani SK. (2019) Performance evaluation of deep neural ensembles toward malaria parasite detection in thin-blood smear images. PeerJ 7:e6977 https://doi.org/10.7717/peerj.6977
The datasets are available at cell_images.zip, the codes at malaria_cell_classification_code.zip and the Patient-ID to cell mappings for the parasitized and uninfected classes at patientid_cellmapping_parasitized.csv and patientid_cellmapping_uninfected.csv respectively.
Contact for more information: Dr. Stefan Jaeger